Previously healthy 57yo woman comes in 2 month history of vulvar itching. otherwise asymptomatic takes no meds. menopause occurred 7 years prior. not bee sexually active for 10 years. exam shows a 1x1.5cm ulcerated lesion in inner right labium majus surrounded by mild erythema. no other lesions noted. no inguinal adenopathy. diagnosis?

Yes, this is very true. specifically causing damage in the  dentrite. 

Takayasu does not cause late puberty

The answer you're looking for is washing your hands. "at this late date, we all expect our doctors to wash their hands before examining us or performing an operation in order to prevent the spread of infection. surprisingly, physicians did not begin to acknowledge the lifesaving power of this simple act until 1847.it was then that dr. semmelweis began exhorting his fellow physicians at the famed vienna general hospital (allgemeines krankenhaus) to wash up before examining women about to deliver babies. his plea was far more than aesthetic; it was a matter of life and death and to prevent a deadly malady known as “childbed” or puerperal (from the latin words for child and parent) fever." 

during longer space exploration trips, crewmembers may develop vision impairment risks and short-term cardiac atrophy or a decrease in the size, strength, weight, and activity of the heart during space flight because they can experience microgravity. in addition, the long-term medical condition is loss of bone mineral density and radiation exposure.