Local anesthetics block voltage-gated na+ channels, but they do not block mechanically gated ion channels. sensory receptors for touch (and pressure) respond to physical deformation of the receptors, resulting in the opening of specific mechanically gated ion channels. why does injection of a local anesthetic into a finger still cause a loss of the sensation of touch from the finger?
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Local anesthetics block voltage-gated na+ channels, but they do not block mechanically gated ion cha...
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