Isabelle has forgetting things lately and her friends and family have been angry at her. today she feels as if she's going to do something wrong no natter how hard she tries. she has decided to play it safe and stay indoors even though there are many things she would like to do with her friends. what has most likely happened to isabelle

Adouble-blinded trial for a new indication is conducted under an ind comparing two (2) marketed drugs, at twice the approved prescribed doses. on day 2, subject 603 had difficulty breathing. although it was life-threatening initially, subject 603 was treated and discharged directly from the emergency department after complete recovery. on day 5, subject 20 had a headache, which led to hospitalization and required blood pressure lowering medications. these episodes cannot be explained on the basis of the pharmacological property of either drug or the subjects' medical histories. the investigator would submit an sae report for