What is the relationship between weight reduction and hormones

Hormones send signals frequently to your metabolism , one commonly known hormone associated with weight is Leptin, which is what sends signals to your brain letting you know that you are full. However, if you eat too much fat that could create excess Leptin, the brain will become resistant to this hormone that signals you to eat which will cause you to eat more and gain more weight after you begin to lose the sensation of being full.
And as a first mention can affect your metabolism, but another major hormone that affects this is cortisol which helps regulate the metabolism and manage stress , if there’s too much stress on the body it could caused an increased appetite as well as increased fat on the abdomen (stomach.)

In addition to these hormones, thyroid hormones also regulate the metabolism. When the hormones in the thyroid gland are too much or too little it can result in extreme weight gain or weight loss as seen in patients with either hypothyroidism or hyperthyroidism.

Ithink the correct answer would be that since the disease is passed by a hand shake and can be cured with antibiotics that it could be an infection. an example could be that once when i was working in a bush camp, i got blood poisoning from blood blisters that got infected. our cook did not wash his hands after going to the bathroom and he passed staphyloccus on to the crew he fed. one other person also got a bad similar infection on the side of his face. i had to be rescued by helicopter and taken to the hospital so i wouldn't die!