Which items are described by the geographic theme of human-environmental interaction? France is divided into twenty-two regions. The Pyrenees Mountains form the border between France and Spain. A highway through Mount Blanc connects Italy and France. The Channel Tunnel connecting the United Kingdom and France reduced travel time between these nations. France's land borders are Belgium, Germany, Luxemburg, Switzerland, Italy, and Spain. Land has been cleared to make room for France's famous vineyards.