What are some of the factors that could contribute to an area being sparsely populated?

little transportation, little industry, no huge businesses, extreme climates like the dessert, or unreliable food/water supplies.

Explanation:

I hope this helps! :)

within these regions are all the major types of biomes in the world. a biome is a community of animals and plants spreading over an extensive area with a relatively uniform climate. some diverse biomes represented in north america include desert, grassland, tundra, and coral reefs.