One of the themes of macbeth is evil.

The main theme of Macbeth—the destruction wrought when ambition goes unchecked by moral constraints—finds its most powerful expression in the play's two main characters. Macbeth is a courageous Scottish general who is not naturally inclined to commit evil deeds, yet he deeply desires power and advancement.

Manga is a japanese comic book (sort of) while anime is the a sort of show on a screen. most animes were originally manga though