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How does the passage expand on the central idea "the plague was the biggest killer in elizabethan england"? answer is: very enty-three ncluding ethem will ring it with fire ivice of the it explains that many people died because medicines and medical practices were not effective. it explains that people were not taking the medical advice of doctors it explains that the physicians gave up on trying to stop the spread of disease. dethan england, ian mortimer it explains that the medicines and medical practices of the time saved lives.