What do you think the biggest obstacle was in Native American and US Government relations?

As a Native American myself i would say,

The new US Government was careful not to antagonize the Indians and sought to treat them with mutual respect.  This is evidenced in early treaties where the term “Red Brothers” was used to convey this sentiment of equality.   By 1800 interaction between the Indian and white settlers had become quite common through trade.  Many Indians traded for household goods, traps and tools.  The US became concerned about the cultural differences and sought to improve the Indian station in life by providing education.  The United States no longer feared the Indian but rather took a paternal position toward the Indians and the treaty language reflected this when the Indian was referred to as “Our Red Children.”

you cant make me do anything i don't want to do michael yelled.