When done-cigarettes producers have to apply to the fda for a review of their product?

Tobacco use is the single largest preventable cause of disease and death in the United States.1 Since 2009, FDA has regulated cigarettes, smokeless, and roll-your-own tobacco. FDA finalized a rule, effective August 8, 2016, to regulate all tobacco products. For background information on this milestone in consumer protection,

Explanation:

the answer is "began" because it is a action that can be done

synomenous

sry cant spell