Descriptions of enzyme mechanisms often contain the terms reaction intermediate, transition state, and transition state analogue. The terms intermediate and transition state both describe chemical species along the reaction pathway, but there are important distinctions between the two. Transition state analogues are often used in enzyme mechanism studies. Match the phrases to the term that they describe. Intermediate Transition state analogue Transition state
1. Compound designed to mimic the the structure of a transition state
2. Contain partially formed and partialy broken bonds.
3. Often serves as a potent enzyme inhibitor.
4. Any reaction pathway species with a finite (>10^-13s) lifetime.
5. Example include Es(enzyme substrate complex andEP( enzyme product complex)
6. Some are stable enough to be detected and structurally charactreized.
7. Hypothetical maximum energy species of a reaction pathway does not have a finite lifetime.