An aqueous suspension dosage form is prepared which contains 150 mg of drug per ml of suspension. The equilibrium solubility of the drug in water is 11 g/L. The drug in solution undergoes first-order decomposition and decomposes to 75% of the initial concentration in 400 hours.
A) Determine the zero-order rate constant.
B) Assuming that the shelf-life of a drug is t10%, calculate the shelf-life.
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An aqueous suspension dosage form is prepared which contains 150 mg of drug per ml of suspension. Th...
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