The SNArreaction requires 1 mmol methyl 4-fluoro-3-nitrobenzoateand 2 mmol of 4-chlorobenzyl amine. Calculate the mass (mg) of both reagents.(2

Mass of methyl 4-fluoro-3-nitrobenzoate = 199 mg;

Mass of 4-chlorobenzylamine = 282 mg

Explanation: The mass and mol of a molecule is related by its molar mass, which is given in g/mol.

The molar mass of methyl 4-fluoro-3-nitrobenzoate, which has molecular formula: is:

 = 12.8 + 6.1 + 19 + 14 + 16.4 = 199 g/mol

Since it is asking in mg: MM = 199.10³mg/mol

For 4-chlorobenzylamine, with molecular formula :

= 12.7 + 8.1 + 35 + 14 = 141 g/mol

In mg: MM = 141.10³mg/mol

The reaction requires 1 mmol of , then its mass is:

m = 1.10⁻³ mol * 199.10³mg/mol = 199 mg

For , it requires 2mmol:

m = 2.10⁻³ mol * 141.10³ mg/mol = 282 mg

For the SNAr reaction, it is necessary 199 mg of methyl 4-fluoro-3-nitrobenzoate and 282 mg of 4-chlorobenzylamine

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