Which of the following statements describes how enzymes differ from ordinary chemical catalysts?
Enzymes are inorganic in nature.
Enzymes catalyze select chemical reactions.
Enzymes bind their substrates for a brief time.
Enzymes increase the rate of a chemical reaction.

- "the choice that is not an indicator of a chemical change is "state of matter changes". more common than not, chemical reactions produce energy in the form of light or heat. along with energy, they also produce a new substance called the product that could be in any state of matter (solid, gas, or liquid)."

the answer your looking for is c).