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Chemistry, 02.04.2020 18:23 shakira11harvey6
Acid chlorides react with Grignard reagents to yield tertiary alcohols, two equivalents of Grignard reagent are required. The first equivalent reacts in a typical nucleophilic acyl substitution reaction to give a ketone. This ketone, however, is itself reactive in the Grignard reaction. Thus, the second equivalent adds to the ketone carbonyl carbon. Subsequent protonation yields the tertiary alcohol.
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Acid chlorides react with Grignard reagents to yield tertiary alcohols, two equivalents of Grignard...
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