The transcription factor ap-1 is a heterodimer consisting of c-jun and c-fos. c-jun and c-fos are soluble proteins that can be localized to either the cytosol or nucleus of a cell. c-jun and c-fos dimerize through a leucine zipper motif. in a leucine zipper motif, every 7 amino acid residues, or 2 full turns of an alpha helix, are leucine resides. leucine and other amino acids on one face of the helix come together to form an opposite alpha helix that has a similar arrangement of leucine and other amino acids. which solvent would be least favorable for c-fos/c-jun dimerization?