The benefit of measuring the initial rate of a reaction v₀ is that at the beginning of a reaction: a) [es] can be measured accurately. b) changes in [s] are negligible, so [s] can be treated as a constant. c) changes in km are negligible, so km can be treated as a constant d) v₀ = . e) varying [s] has no effect on v₀

C) changes in Km are negligible, so Km can be treated as a constant

Explanation:

Hello,

Biochemical reactions have been widely modeled by Michaelis through His well-known equation:

Thus, in order to correctly assure the value of the initial rate of the reaction allows the calculation of Km, therefore changes in Km are negligible, so Km can be treated as a constant as long as it is the substrate concentration at half of the maximum rate, in fact, Km is known as the Michaelis constant.

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