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Chemistry, 19.12.2019 00:31 icantspeakengles

How should the nutritionist explain why fats cannot be directly converted into carbohydrates?

a. glucose can be created from pyruvate by gluconeogenesis. however, pyruvate generated from fats occurs via the citric acid cycle. because carbons from fats must enter the citric acid cycle as acetyl coa first, fats can only indirectly become carbohydrates.
b. during gluconeogenesis, glucose is created from oxaloacetate. however, oxaloacetate generated from fats occurs via the citric acid cycle. because carbons from fats must enter the citric acid cycle as acetyl coa first, fats can only indirectly become carbohydrates.
c. glucose can be created from pyruvate via gluconeogenesis, and fats enter the citric acid cycle as acetyl coa. however, any acetyl coa entering the citric acid cycle must be released as co 2 . thus, fats cannot be used for synthesis of carbohydrates.
d. the concentration of various intermediates control the activity of metabolic enzymes. although oxaloacetate is converted into glucose via gluconeogenesis, pyruvate carboxylase is inhibited by oxaloacetate concentrations in the fasting state.

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