Saturated drug is encapsulated in a membrane-controlled reservoir device. the shape of the device is cylindrical. the total amount of released drug at time t can be calculated according to the following equation. m_t=(2πhdkc_s)/(ln(r_0/r_i)) t the saturated drug concentration in the polymer matrix is 150 mg/cm3. the diffusion coefficient of the drug d is 2.2×10-10 cm2/s, and the partition coefficient k is 10. the length (h) and diameter (2r0) of the device are 1 cm and 500 µm respectively. the saturated drugs are in a cylindrical space with a diameter (2ri) of 200 µm. 1) calculate the amount of released drug in 48 hours. (25 points) 2) in order to apply this delivery system to children, the release rate should be reduced by 60%. how to design the device if the volume of the space for concentrated drugs and the volume of the device are both unchanged? (25 points)
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Chemistry, 22.06.2019 12:10
Achemistry student needs to standardize a fresh solution of sodium hydroxide. he carefully weighs out of oxalic acid , a diprotic acid that can be purchased inexpensively in high purity, and dissolves it in of distilled water. the student then titrates the oxalic acid solution with his sodium hydroxide solution. when the titration reaches the equivalence point, the student finds he has used of sodium hydroxide solution.calculate the molarity of the student's sodium hydroxide solution. be sure your answer has the correct number of significant digits.
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Chemistry, 23.06.2019 03:30
The molar mass of nickel(ni) is 58.7 g/mol. how many moles are in an 88 gram sample of nickel?
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Saturated drug is encapsulated in a membrane-controlled reservoir device. the shape of the device is...
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