Using lexicomp, briefly compare the stated pharmacokinetic parameters of acetaminophen and ibuprofen in the following three questions: [lexicomp is available as a link from the pharmacology site on sakai and also from online resources on the school website]
a. in healthy adults, comparing acetaminophen and ibuprofen, which pharmacokinetic parameters are similar and which are significantly different?
b. how does recommended dose and method for determining dose differ from adult dosing when considering healthy children between 6 months old and 15 years old?
c. you have a patient with renal impairment who requires post-operative pain medication. according to lexicomp, how should acetaminophen therapy be adjusted to account for this condition and which other easily adjustable parameter(s) might you consider modifying?