Consider phosphofructokinase, which statement is true? group of answer choices
none of the above.
high atp inhibits the enzyme; fructose-2,6-bisphosphate activates the enzyme.
low atp activates the enzyme; fructose -2,6-bisphosphate inhibits the enzyme.
high atp activates the enzyme; fructose -2,6-bisphosphate inhibits the enzyme.
fructose -2,6-bisphosphate and atp inhibit the enzyme.

High ATP inhibits the enzyme; fructose-2,6-bisphosphate activates the enzyme.

Explanation:

PFK-1 inhibitors are ATP and Citrate which is an intermediate metabolite of the aerobic cycle while the activators responsible for reversing such inhibition caused by ATP are ADP, AMP and Fructose -2,6-bisphosphate. The lats one is a powerful activator of PFK-1 but in the liver.

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