Chemistry, 01.10.2019 00:20 isabelsmhl
For this exercise, picture a voltage clamp that shifts from vm=-60 mv to vm= 15 mv. at first, the clamp is performed with the normal composition of [na+]i=15 mm and [na+]o= 180 mm. the experiments are performed at a temperature of 25°c.(a)the early current is carried by which ion and crossing in which direction? (b)thesteady-state current is carried by which ionand crossing in which direction? (c)if the voltageclamp is repeated such that the sodium current is abolished, what extracellular medium changes are necessary? be specific and quantitative.(d)if the voltageclamp at vm= 15 mv is conducted with 10% sodium seawater (i. e. [na+]o= 18.0 mm), how does the sodium current magnitude and time course compare with that under normal conditions? be specific and quantitative.(e)how does the potassium ion flow compare during the voltage clamp under normal, zero sodium flux, and10% sodium seawater conditions?
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For this exercise, picture a voltage clamp that shifts from vm=-60 mv to vm= 15 mv. at first, the cl...
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