Which chemicals are major contributors to ozone layer destruction? select two answer choices.

phosphorus
nitrogen
bromine
chlorine
carbon dioxide
methane

Chlorine and bromine

Explanation: The chlorine and bromine acts as reactive gases and destroy the ozone  present in the stratospheric ozone.

The ozone layer is present in the stratosphere to filter the harmful rays of the sun that is harmful for the people living on earth.

A chlorine or bromine molecule can destroy thousand of the ozone molecules before it leaves the stratosphere.

So, a single bromine or chlorine atom can affect the ozone layer.

i believe you are right for all except the 3rd ( look at sqdancefan his answer is much better)