Factors that limit a technological design are called constrains. but why?

The factors that limit a technological design can be physical and social. The physical limitations are constraints due to nature itself. They  include natural laws and properties of materials.

Social limitations on the other hand are limitations that arise as a result of the society we are living in and include the ease of use, safety, attractiveness, and cost.

the major pests we deal with are insects, weeds and fungal diseases. a pesticide is a product, whether organic or chemical, used to kill the target pest. there are other techniques gardeners should use that can prevent the severe infestations that make the use of pesticides necessary

it can be observed without changing the identity of the object.

it depends on what substance you're talking about as well as many other factors. in quantum mechanics, the observation of particles affects the observers ability to measure certain properties. for example: you can know the velocity of a particle, but you can't know it's position; or you can know it's position, but not it's velocity. it's like trying to find out where a grain of sand is by throwing other grains of sand at it. once you find out where it is, it's been moved. it's also like trying to find an answer to the question of whether or not a tree falling in a forest makes a sound if nobody is there to hear it. paradoxically, the only way to find out is to be there and hear it.