Aperson breaks a bone and has it set and put in a cast, but it does not heal. what would be the best thing for the doctor to investigate as a possible cause? the bone marrow, which should have supplied the growing bone with blood the ligaments, which should have held the ends of the bone together while it mended the synovial fluid in the bone, which should have carried nutrients to the growing bone the osteoblasts, which should have been building the new bone

The osteoblasts, which should have been building the new bone

Explanation:

Osteoblast are the cells that build bones by secreting the extracellular matrix for bone tissue. These cells secrete components such as collagen fibres and inorganic electrolytes that together make the matrix of bone tissue. Absence or inactivity of these cells could prevent the formation of new bone after fracture. Hence, doctors should target osteoblasts.

Explanation:

The osteoblasts are the bone cells that are capable of forming the new bones. They develop from bone marrow. They have only one nucleus. These cells work in teams so as to build a new bone. They produce a new bone which is called as osteoid which is made up of protein and bone collagen. The absence or lack of production of oestoblasts will restrict the formation of new bone after fracture. Thus the doctor must look up the activity of osteoblasts.