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In humans, albinism is caused by loss-of-function mutations in genes involved in the synthesis of melanin, the dark pigment in skin. only people homozygous for a loss-of-function allele (genotype aa) have the albino phenotype. in americans of northern european ancestry, albino individuals are present at a frequency of about 1 in 10,000 (or 0.0001). assuming that genotypes are in hardyâweinberg equilibrium, what is the predicted frequency of caucasians in the united states who carry a single allele for albinism?
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