Processes that regulate cell division in mammals include:

  The process that involves regulation of cell division in mammals includes:
Rapid production of cyclin proteins that activate CDK enzymes;
The activated cyclin CDK complexes trigger cell cycle events.
Different cyclins and CDKs act at different stages of the cell cycle to promote cell division.
The rapid degradation of cyclins after CDK activation. 
Through phosphorylation, Cdks signal the cell that it is ready to pass into the next stage of the cell cycle. The Cyclin-Dependent Protein kinases are dependent on cyclins, another class of regulatory proteins. Cyclins bind to the Cdks, activating the Cdks to phosphorylate other molecules. 

It allows water to resist freezing and thawing cycle.