The only process that can change a gene's dna and therefore give rise to new genetic variations in a species is

Hello Littlefoot2645. I do believe the answer would be that of the process of "mutation," thus it occurs by human interference, specifically, although, initially, naturally-speaking, only occurring by natural selection in onslaught of period time frames.

Hey there!

The only process that can change a genes DNA and therefore give rise to a new genetic variations in a species is a mutation.

Hope this helps you.
Have a great day!