Depletion of nonrenewable resources is often a result of

Scarcity

non-renewable resource. - once used it does not grow or come back or if it does come back, it will take a very long time.

The result of human activities that adversely affects earth's natural resources is pollution. Be it air pollution, water pollution, or land pollution. 

Land pollution happens when humans do not properly dispose of their garbage. 
Water pollution happens when chemical or dangerous foreign substances are introduced to water. 
Air pollution occurs when the chemical composition of air is imbalanced. This is caused by releasing particles into the air from burning fuels, and other dangerous gases.

All these pollutions are consequences of irresponsible human actions. If we continue to pollute our air, land, and water, we will experience global warming, lesser food sources, and acquire diseases that are caused by breathing, eating, and drinking contaminated natural resources.

They don’t store and transmit heredity