In contrast to a disease, a disorder is generally defined as 1.any genetic mutation. 2.an untreatable condition. 3.an illness with specific symptoms. 4.any abnormality of body function.

The appropriate answer is 4. any abnormality of body function. A disorder occurs when any specific part of the body does not function the way it normally should. A disease is a pathological condition that is not caused by a physical injury.
Not all genetic mutations are or lead to disorders and some are treatable usually by corrective surgery or other methods.

Mitochondria is the cell organelle that produced the energy that is needed in the body system in form of atp, that is why it is called the power house of the cell. energy is needed by the living organisms to carry out the activities which sustain life.  if the mitochondria is destroyed atp will not be produced. if the mitochondria is destroyed, energy production will stop and the affected living organism will not have the energy to carry out the necessary life processes; this will lead to the death of the organism.