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Biology, 27.08.2019 20:30 trintrin227

Agene that codes for one of the polypeptide chains of the blood proteins hemoglobin lies on chromosome 11 in humans. a substitution mutation in that gene causes the amino acid valine to be incorporated into hemoglobin in a place where glutamic acid would normally lie. the result is sickle cell disease. explain how a change in a single base in dna can bring about such a serious disorder.

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