The venom of the black widow spider bite causes to be released continuously by motor neurons, causing severe muscle spasms.

It causes acetylcholine. An acetylcholine is an element that is established amid the nerve synapses or breaches amid nerve cells. Once stimulated, it origins the tightening of skeletal muscles and stimulates glandular roles in the endocrine system and it shows an essential role in the sign of muscle undertaking, awareness of pain, knowledge and memory development, the directive of the endocrine system and rapid eye undertaking sleep sequences in which when unconstrained continuously by motor neurons it will lead to severe muscle spasms.