In many animal cells, the uptake of glucose into the cell occurs by a cotransport mechanism, in which glucose is cotransported with na+ ions.

   outside cell:
 [Na+] high
 [glucose] low
   transporter: glucose and Na+ go down
   inside cell:
 [Na+] low
 [glucose] high
   1. Na+ moves down its electrochemical gradient.
 2. Glucose moves against its concentration gradient.

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