Apatient will be taking amiodarone [cordarone]. which baseline tests are necessary before this medication is started? (select all that apply.)

the oldest known insects are believed to live around 400 millions ago as suggested by the fossil records.   some plants having woody stems also evolved during this time.

after the evolution of insects the first four legged species or the tetrapods evolved in shallow freshwater habitats from the intermediate species approximately 397 million years ago. the tetrapods went on conquering the land giving rise to amphibians, reptiles, mammals and birds.

the major split in tetrapods first occurred 340 million years ago branching off from amphibians.

363 million years ago when the carboniferous period began the insects started roaming on land and taking flights, following which the four limbed tetrapods adapted in the terrestrial habitat.

we solve the problem using the hardy-wineberg equation.

let us start with the homozygous recessive proportion of individuals with sickle cell anaemia,

we have the proportion as q² = 0.25.

∴ q = 0.5 (frequency of hbs in population)

further,

solving for the frequency of normal cell by using the fact that,

p + q = 1

∴ p = 1 - 0.5 = 1 - 0.5 = 0.5

now we can calculate 2pq in p² + 2pq + q², which is the frequency for heterozygous carriers of sickle cell anaemia,

∴ 2pq = 2 x 0.5 x 0.5 = 0.5

and the homozygous normal cell individuals proportion is given by the expression,

∴ p² = 0.5² = 0.25

hence, the carriers for sickle cell anaemia are in proportion, 0.5, or 50%.