Which of the following distinguishes the function of dasatinib from the function of imatinib? Dasatinib binds BCR-ABL in its inactive and active conformation, while imatinib binds BCR-ABL only in its inactive conformation. Dasatinib is a competitive inhibitor of BCR-ABL, while imatinib is a noncompetitive inhibitor of BCR-ABL. Dasatinib binds in the ATP-binding pocket of BCR-ABL, while imatinib does not. Dasatinib prevents BCR-ABL from phosphorylating substrates, while imatinib blocks other functions of BCR-ABL
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Which of the following distinguishes the function of dasatinib from the function of imatinib? Dasati...
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