In rodents, certain stimuli can induce a signaling pathway that ultimately causes the release of the nonpolar steroid hormone corticosterone from the adrenal gland into the blood. Corticosterone can bind to intracellular receptors in kidney cells. After binding corticosterone, corticosterone receptors function as transcription factors by binding DNA and activating gene expression. a) Corticosterone has a specific three-dimensional shape that is essential for proper binding to its receptor.
a. true
b. false
b) Corticosterone can have indirect effects on cells that do not have corticosterone receptors.
a. trueb. false
c) Corticosterone receptors can bind to any DNA sequence in order to activate transcription.
a. trueb. false
d) Corticosterone can enter target cells through simple diffusion across the plasma membrane.
a. trueb. false
e) Under normal conditions, corticosterone levels in the blood will eventually return to their original levels once the initial stimulus is removed.
a. trueb. false