Two transcription activators cooperate to recruit a coactivator to a cis-regulatory sequence and activate transcription of a nearby gene. If each of the activators increases the affinity of the coactivator for the reaction site (and therefore the rate of transcription) by 100-fold, how much would you expect the affinity to increase when both activators are bound to DNA compared to when none is bound

In response to framton's dialogue about his health issues, mr. sappleton replies: "no? " said mr. sappleton, in a voice which only replaced a yawn at the last moment. then she suddenly brightened into alert not to what framton was saying. what does this statement reveal about how mrs. sappleton feels about framton? a) she finds him boring. b) she's happy he came by. c) she finds him annoying. d) she feels sorry for him