Type 2 diabetes is an example of a disease that results from the loss of a normal signal transduction pathway. In a person who does not have type 2 diabetes, the pathway begins when insulin binds to the insulin receptors on the surface of a cell. This initiates a signal that tells the cell to synthesize glucose receptors and transport them to the cell membrane where they are to become incorporated. Once incorporated, they allow the cell to take in glucose present in the extracellular medium. Required:
Justify the claim that changes in normal signal transduction may alter cellular response by describing how type 2 diabetes results from dysfunctional signal transduction.