Match each immune cell with the method it uses to neutralize a pathogenic microbe that has infected a human - Cytotoxic T cell - Helper T cell - B cell - Natural Killer Cell - Macrophage - Mast Cell A. kills infected human cells after recognizing antigens displayed on MHC class 1 B. does not directly kill microbes; after recognition of a specific antigen displayed on MHC Class 2, it secretes molecules that help other cells to do so. C. phagocytoses microbes after recognizing specific antigens; secretes antibodies D. kills virus-infected human cells by releasing perforin and granzymes. E. Phagocytoses microbes after recognizing PAMPs; acts as an Antigen Presenting Cell to activate another type of immune cell F. Does not directly kill microbes; secretes histamine to initiate an inflammatory response.

Cytotoxic T cell - kills infected human cells after recognizing antigens displayed on MHC class 1 B.

Helper T cell - does not directly kill microbes; after recognition of a specific antigen displayed on MHC Class 2, it secretes molecules that help other cells to do so.

B cell - phagocytoses microbes after recognizing specific antigens; secretes antibodies

Natural Killer Cell - kills virus-infected human cells by releasing perforin and granzymes.

Macrophage - Phagocytoses microbes after recognizing PAMPs; acts as an Antigen Presenting Cell to activate another type of immune cell

Mast Cell - Does not directly kill microbes; secretes histamine to initiate an inflammatory response.

Explanation:

T cell are immune-response cells that originate in the bone marrow but migrate and develop in the thymus gland. They are of two classes; Cytotoxic T cells and Helper T cells.

Cytotoxic T cell - kills infected human cells after recognizing antigens displayed on MHC (Major histocompatibility complex) class 1 B.

Helper T cell - does not directly kill microbes; after recognition of a specific antigen displayed on MHC Class 2, it secretes molecules that help other cells to do so.

B cells are formed and develop in the bone marrow. They make antibodies against antigens, and phagocytoses microbes after recognizing specific antigen.

Natural Killer Cells are cytotoxic lymphocytes of the innate immune system. They kill virus-infected human cells by releasing perforin and granzymes.

Macrophages are a type of white blood cells that detects and phagocytoses microbes after recognizing PAMPs (Pathogen-associated molecular pattern) They also act as Antigen Presenting Cell (APCs) to activate another type of immune cell

Mast Cells are cells found in the connctive and they function as part of the immune system of the body. They do not directly kill microbes. They secrete histamine to initiate an inflammatory response.

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