is the process in which action potentials in the nerve fiber lead to action potentials in the muscle fiber. There is then a rapid fluctuation in membrane voltage at the motor end plate, called the end-plate potential. Areas of the sarcolemma near the motor plate have gates that open, moving ions, which causes the potential that excites the muscle fiber. The process begins with a nerve signal stimulating a voltage-gated ion channel to open, allowing the ions to enter the axon terminal. The ions stimulate the release of into the synaptic cleft.

Excitation is the process in which action potentials in the nerve fiber lead to action potentials in the muscle fiber. There is then a rapid fluctuation in membrane voltage at the motor end plate, called the end-plate potential. Areas of the sarcolemma near the motor plate have gates that open, moving ions, which causes the action potential that excites the muscle fiber. The process begins with a nerve signal stimulating a voltage-gated calcium ion channel to open, allowing the ions to enter the axon terminal. The ions stimulate the release of acetylcholine into the synaptic cleft.

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