An individual has a genetic disorder in which their cell is not forming the correct protein structure for the cell membrane to allow entry of a particular ion. doctors have determined that in order to cure this person they need to alter the shape of the protein. which type of regulation of gene expression would have the greatest chance of success

The answer is Post-translational control. 

Post-translational direction alludes to the control of the levels of dynamic protein. It is performed either by methods for reversible occasions or by methods for irreversible occasions. 
Post-translational change alludes to the covalent and for the most part enzymatic alteration of proteins amid or after protein biosynthesis. Proteins are integrated by ribosomes making an interpretation of mRNA into polypeptide chains, which may then experience PTM to frame the develop protein item.

No 1 very mooch