Chronic sleep deprivation is most likely to contribute to the of the immune system.

thrombocytopenia, which is a deficiency in blood platelets, can cause bleeding and bruising in the dermis similar to senile purpura. other possible causes include: exposure to ultraviolet rays and aging skin are common causes of senile purpura. senile purpura may also be a sign of collagen loss in the skin and bones.

the correct answer is 4) heat and pressure

metamorphic rocks arise from transformation of existing rocks types, in a process called metamorphism. during metamorphism the original rock(prolith) change into metamorphic rock by heating (150-200c) and pressure of more than 1000 bar. the original rock can be sedimentary, igneous, or existing metamorphic rock.