Any factor that changes the shape of an enzyme can affect the enzyme's activity. which of the following two factors affect an enzyme's operation the most?

I think you forgot to attach the options along with the question. I am answering the question based on my research and knowledge. the two factors that affect an enzyme's operation the most are temperature and pH level. Enzymes function at at its best when pH is 7.4. I hope the answer helps you.

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