Below is a partial mRNA sequence. Use it to answer the following questions. 5' - GCCGAUCGAACU - 3'
What is the correct reading frame for this mRNA?
5' - G | CCG | AUC | GAA | CU - 3'
If a single base-pair deletion occurred in the part of the gene that corresponds to the mRNA above and the resulting partial amino acid sequence was (N-term-...P-M-N...-C-term), which new partial mRNA sequence would be consistent with this change?
5' - G | CCG | AUG | AAC | U - 3'
Part C
The amino acids in the original partial sequence (N-term-...P-I-E...-C-term) have little to no impact on protein structure and function. However the amino acid sequence near the C-terminal end of the protein is required for normal function. Any amino acid changes in this region of the protein will result in a nonfunctional protein.
Given this information, which reversion mutation in the gene would restore the normal function of the protein?
a. Insertion of 2 base-pairs in the region of the proline codon
b. Deletion of 5 base-pairs in the region of the proline codon
c. Deletion of 2 base-pairs in the region of the proline codon
d. Deletion of 1 base-pair in the region of the proline codon
e. Insertion of 1 base-pair in the region of the proline codon
f. Insertion of 4 base-pairs in the region of the proline codon