Sickle cell anemia is a genetic condition that occurs because of a single point mutation in the DNA gene for hemoglobin. How is this mutation expressed in humans? A.) The protein coded by the DNA has a different amino acid sequence
B.) The chromosome caring this gene changes shape during cell reproduction
C.) The hormones in the bladder change by increase differences in genes
D.) The carbohydrate code by the DNA has a different structure

B.) The chromosome carrying this gene changes shape during cell reproduction

Explanation:

According to this question, Sickle cell anemia is a genetic condition that occurs when the HBB gene that codes for haemoglobin protein undergoes a point mutation. Mutation alters the genetic sequence of a gene.

This mutation expresses itself when the chromosome 11 carrying the mutated gene changes shape during cell reproduction. Normal Red Blood Cell has a disc-shaped structure, however, this mutation causes a change in shape of the chromosome involved.