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Biology, 10.03.2021 19:50 Scourge927

Below is a simplified schematic representation of some of the genetic elements involved in the regulation of Pitx1 gene expression. The large grey rectangle represents the protein-coding region of the Pitx1 gene. The smaller rectangles to the left (b and c) are regulatory switches; each one allows a specific binding protein to interact with it and turn on the Pitx1 gene in a particular tissue. When expressed, the Pitx1 gene is transcribed and then translated to generate the Pitx1 protein. A deletion at the location (a) causes a frameshift mutation.

a) How likely is it that a functional Pitx1 protein would be produced in the jaw?

b) How likely is it that a functional Pitx1 protein would be produced in the pelvis?

(answer likely or not likely for each)

c) Justify your answer in 2-3 sentences.


Below is a simplified schematic representation of some of the genetic elements involved in the regu

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