Consider a population of 1001 gray wolves. In this population, a single locus determines coat color. This locus has two alleles and is incompletely dominant, so that the gray/gray genotype is gray, the gray/white genotype is light gray, and the white/white genotype is white. You observe the following counts of each genotype: 458 (gray/gray), 391 (gray/white), and 152 (white/white). What is the frequency of the white colored allele (give your answer to two decimal places)

Mr. j, age 42, is a construction worker in las vegas. he recently noticed that a mole on his face seemed to be getting larger and darker. at first he did not worry because he was in the sun a lot and assumed the change may have been caused by sunburn. after a month, not only was the mole larger and darker, but it appeared to be “bumpy.” his doctor diagnosed a malignant melanoma skin cancer following biopsy of the nevus. mr. j reports pain in his right shin that does not go away when he puts his feet up or sleeps. discussion questions 1. relate mr. j’s skin changes to the warning signs for malignant melanoma. (see malignant melanoma.) 2. discuss the normal progression of this malignancy. what is the significance of the bone pain that mr. j is experiencing? (see malignant melanoma.) 3. discuss the treatment available for this patient and the prognosis for recovery. (see malignant melanoma.)