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Biology, 26.02.2021 23:40 diwashkandel6pe02af

If a mouse is given a dose of radiation sufficient to destroy its immune system, then injected with purified hematopoietic stem cells, what should happen?

A-

The mouse survives over 3 months and if successful transplantation

of their new HSCs rescues a second lethally irradiated recipient,

they can be considered to have received near pure HSC,

reconstituting their immune system.

B-

The mouse's remaining immune cells will cause a graft versus host

immune reaction, targeting the new HSCs for destruction.

C-

The new HSCs will over proliferate and the mouse will develop

leukemia.

D- the mouse dies as its immune system might attack the HSC.​

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Answers: 1

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