Below is a list of physiological events involved in synaptic transmission. Using your knowledge from class, place the events in the correct order. A. Vesicles filled with neurotransmitter fuse with axon terminal end membrane B. An excitatory post synaptic potential results C. Ligand gated ion channels are stimulated to open D. Neurotransmitter binds to respective receptor E. Ca2 voltage gated channels are stimulated to open F. Action potential travels down the length of an axon G. Ca2 rushes in H. Neurotransmitter is released into synaptic cleft I. Na rushes in J. Action potential is generated at the axon hillock K. Ca2 interacts with docking proteins on secretory vesicle

J. Action potential is generated at the axon hillock

F. Action potential travels down the length of an axon

E. Ca2 voltage gated channels are stimulated to open

G. Ca2 rushes in

K. Ca2 interacts with docking proteins on secretory vesicle

A. Vesicles filled with neurotransmitter fuse with axon terminal end membrane

H. Neurotransmitter is released into synaptic cleft

D. Neurotransmitter binds to respective receptor

C. Ligand gated ion channels are stimulated to open

I. Na rushes in

B. An excitatory post synaptic potential results  

Explanation:

In a chemical synapsis, an action potential travels through the axon up to the axon terminal. In this place, the potential causes Ca2+ voltage-gathered channels to open and Ca2+ to enter the presynaptic terminal. The Ca2+ interacts with the vesicles that contain the neurotransmitters making them go to the presynaptic membrane and fuse with it to release the neurotransmitters. The neurotransmitters are released into the synaptic cleft and bind to the specific receptors in the postsynaptic membrane. The binding of these receptors and neurotransmitters allows the opening of ion channels. As a result, Na+ rushes into the postsynaptic cell, leading to an excitatory postsynaptic potential.

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