How is the inside of the nucleus connected to the cytosol? why is this connection vital for the cell?

try using substitution:

x + y - 6 = x - y. (i'm not giving you the exact answer). since 0 = x - y, then sub 0 in the equation with x - y. combine your like terms, and then use inverse operations, and you'll have your answer.

: -)

genetic variation can be caused by mutation (which can create entirely new alleles in a population), random mating, random fertilization, and recombination between homologous chromosomes during meiosis (which reshuffles alleles within an organism's offspring).